Side Effects of Generic Estrace (Estradiol)

Get emergency medical help for those who have any of these signs of an allergic reaction to Estrace: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop making use of Estrace and call your doctor at once when you have a significant side effect like:

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unusual vaginal bleeding (particularly if you are past menopause);
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chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
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sudden numbness or weakness, particularly on 1 side of the body;
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sudden severe headache, confusion, troubles with vision, speech, or balance;
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stabbing chest pain, sudden cough, wheezing, rapid breathing, fast heart rate;
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discomfort, swelling, warmth, or redness in 1 or both legs;
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nausea, vomiting, loss of appetite, increased thirst, muscle weakness, confusion, and feeling tired or restless;
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a lump in your breast;
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feeling like you may pass out;
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pain, swelling, or tenderness inside your stomach; or
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jaundice (yellowing of the skin or eyes).

Much less serious Estrace side effects might contain:

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mild nausea, vomiting, bloating, stomach cramps;
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breast discomfort, tenderness, or swelling;
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freckles or darkening of facial skin;
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loss of scalp hair;
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vaginal itching or discharge; or
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changes within your menstrual periods, break-through bleeding.

This isn't a total list of side effects and other people may possibly occur. Call your physician for medical advice about side effects.

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